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Daily Journal with Mitochondrial Myopathy

Day by Day with a Movement Disorder

My Journey with a Mitochondrial Disease - "But they that wait upon the LORD shall renew their strength; they shall mount up with wings as eagles; they shall run, and not be weary; and they shall walk, and not faint." Isaiah 40:31 KJV

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Diagnosis in 2006 - Parkinson's Disease and Peripheral Neuropathy, then in 2007 - Essential Myoclonus. Finally in 2011, after a muscle biopsy, I was diagnosed with Mitochondrial Myopathy as well as Peripheral Neuropathy.

Share my journey - coping with the testing, the medicines, nutrition, digestion problems, exercise, the emotions, uncertain diagnoses and no telling what else!

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Sleep Continues to Be Scarce

Day by Day with a Movement Disorder Posted on July 8, 2007 by DBJuly 8, 2007 4

The insomnia is continuing to bother me just about like it has been for several months now. I’m still having constipation problems, too. I’ve been on the Miralax continually now, but when I had to stop taking the Zelnorm, it began to gradually give me trouble again. I’ve been using the glycerin suppositories regularly now for the last week, but the problem isn’t resolved yet. I’m already on a Metamucil capsule every day, besides the Miralax, so I hate to add any more oral medicine for it, for fear it will suddenly work too well. The only other Parkinson’s thing that is going on with me right now is a very stiff neck. I have had like a crick in my neck now for several days, from a very tight muscle, that I just don’t seem to be able to stretch out or limber up. I’ll just have to keep exercising it, and hope for the best.

We had an absolutely glorious drizzly rain all day long yesterday, and I thank God for that. We need about a week of that kind of rain to make a dent in our drought situation, but it’s better than nothing. Our grass finally looks like grass again.

They are supposed to come finish the garage tomorrow, but it looks like it might be raining. That’s OK. We need the rain worse than we need the garage to be finished. We need to put another coat of water sealer down on the garage floor, anyway, before we start putting stuff in it.

Once we can use the garage for storage, we’ll start bringing the furniture that our DD does not want to keep from their house down here. Also, we have stuff in our basement that we can’t get to because it’s in such a mess. Once we have a place to store it elsewhere, we can start emptying the basement of things and get the good stuff out of our way temporarily. Then we’re going to have to make several trips to the dump!! We used to have a landfill dump here in our town, but it was moved to the other side of the county a long time ago.

That wouldn’t have been so bad, but our town garbage collection rules call for household garbage only. They won’t pick up anything that won’t fit in a garbage bag. So, over the years, as things broke, like the washing machine, it just got stuck in the basement. Now we can hardly move down there. Oh, and the nearest Thrift Store won’t pick up the appliances, either. There are certain disadvantages to living out in the boonies, that’s for sure.

DH won’t let me go down in the basement, as he’s afraid I will trip over something or lose my balance trying to walk around all the stuff. I really do think he’s being over protective, but I’ve done as he asked, and stayed out of it. I’m itching to get it cleaned out, though, and it bothers me that I can’t just go down there and work on it if I want to. As it is, I’m stuck with his idea of when it will get done, and his timetable is a lot slower than mine LOL!! C’est la vie. That’s what being married is all about – the give and take of blending two different people’s habits and problem solving techniques together. I just need to work on my patience a little more, that’s all.

Posted in Uncategorized | Tagged balance, Bowel Retraining, elimination difficulties, exercise, glycerin suppositories, house cleaning, insomnia, Metamucil, Miralax, Parkinson's, remodeling, Zelnorm | 4 Replies

Still NO Sleep

Day by Day with a Movement Disorder Posted on June 10, 2007 by DBJune 10, 2007 6

Insomnia is turning out to be my biggest problem right now, because it effects my stamina and mental agility as the day wears on. I start out each morning all fresh and energetic, even with only 4 hours sleep. I’m wide awake and rarin’ to go! But I fizzle. Not surprising considering it’s been over a month since I’ve had more than 4 hours a night. I doze in the car when we go anywhere, but other than that, there’s nothing.

My Neurologist appointment is coming next week, and he had mentioned doing a sleep study. I think it’s time, don’t you?? I can’t imagine what he can do about it, though, as I’m comfortable in the recliner, and if I snore, there’s no one nearby to tell me about it LOL. I do hear my DH sawing away in the bedroom, though. Ah! Maybe HE’s the culprit!! ROTFL

I’m really proud of how much stronger physically I am right now, and I’m determined to keep up the good work. I’m doing the Tai Chi almost every day, which definitely improves my balance, walking about 6000 steps on average, lifting 1 lb weights to do the arm exercises, and working around the house more than I have in a long time.

We’re about to close on Daddy’s house, so that will be out of the way. That leaves his car and all the stuff in the house to get rid of, plus some small insurance policies to deal with. UGH!

I continue to stay behind on all my computer work, but the eBay business is picking up, now that I’m listing new items every day. Maybe in the year 2020 I’ll have all of the things we have been buying at Estate Sales sold. HA! Maybe … but we keep on buying, ’cause that’s the fun part for us, as we do that together. One step forward and two steps back! All the online part is strictly my doings. Hubby can’t stand computers.

I really do miss all of you, but I just can’t work it all in. I don’t think I think as fast as I used to.

Posted in Uncategorized | Tagged balance, computer addict, eBay, exercise, Friday Date Day, insomnia, Neurologist, Quality of Life, settling an estate, Tai Chi | 6 Replies

Decided Against It

Day by Day with a Movement Disorder Posted on May 28, 2007 by DBMay 28, 2007 6

I do appreciate the feedback you gave me on the decision about joining the St. Vincent’s facility, but we finally decided not to do it at this time. Time was, after all, the deciding factor. It was going to eat up about 3 hours each day I went, and to get any good out of it, I would have to have gone at least 2 days a week, if not 3. I think I can accomplish just about as much with home exercise equipment and our time at the walking track, which is about 5 minutes from home. Of course, in this day and time, we have to take gas prices into account too, and we do live a long way from any of these kinds of sports facilities, with some really bad traffic to contend with both ways.

I continue to accomplish more and more when I exercise in the mornings, but I’m paying for it each night with a lot of sore muscles. DH fusses at me for over doing it, but it doesn’t ever seem like I am at the time. It’s only later in the day that I realize I’ve over taxed my muscles. I think some of this pain I experience is coming from the Peripheral Neuropathy, particularly since I went off the Cymbalta. My Neurologist wasn’t the least concerned about me taking it in conjunction with the Zelepar, even though the Pharmacist had warned me about the combination. So, I may yet go back on it. But for now, I’m still adjusting to adding the Requip back to my meds, so I don’t want to add 2 new drugs at the same time.

The Requip is beginning to upset my stomach, just the way it did last time. I’m having lots of heartburn and belching a lot. Nothing else has changed, so it has to be the culprit. I’ll put up with it if it doesn’t get much worse than this, but I’m still planning to ask for the Neupro patch when I go back to Dr. S in June.

Just to document where I stand physically:

I can now sit down and stand up from a straight chair without using my arms, at least in the morning. I can’t by the evening, though. Sofas and soft chairs I haven’t mastered yet. I can walk over 3000 steps a day on the pedometer most days. I’ve put the handicap toilet seat away for now, as I can deal with the standard one, as long as I have the sink cabinet to hold onto. I’m still using the cane when we go to yard sales and such, where the terrain is unknown, and I still don’t go up and down flights of stairs if I can avoid it. Crouching down to get things in and out of my kitchen cabinets is difficult, so I usually depend on DH to do that for me. I lose my balance too easily, particularly with something in my hands. My core muscles, those of the trunk, are definitely getting stronger as I continue to exercise, as I can now lift my behind when I do what’s called the Bridge. It’s a simple exercise, really. All you do is lie on your back, feet on the floor, with your knees raised, and try to lift your bottom. Until recently, I couldn’t lift more than a half inch or so, but now I’m coming completely off the floor.

I’m doing the Tai Chi short form almost every day now, and I’m getting pretty good at it again. My balance continues to improve.

The biggest problem I am having right now, I suppose, is the insomnia. As soon as I started back on the Requip, it started back again. I haven’t been able to sleep past 3:00 AM for some time now. I get a lot done on the computer, but I really need the sleep! I’ve tried napping later in the day, but that doesn’t work unless I’m in the car. Then I can doze off almost instantly ;).

So, I am progressing, but I have lots of room for improvement. Eating healthy foods and exercising are just as much medicines for me as anything that comes in a bottle!

Posted in Uncategorized | Tagged balance, cane, drug interaction, exercise, gas, GERD, insomnia, nausea, nutrition, peripheral neuropathy, Physical Therapy, Quality of Life, stomach, Tai Chi | 6 Replies

Starting Requip Again – Stopped Physical Therapy

Day by Day with a Movement Disorder Posted on May 8, 2007 by DBMay 8, 2007  

Yesterday was my last time for Physical Therapy on my knee for now. I called my insurance company, and they only allow 15 PT visits a year, unless THEY approve the extra ones, and I’ve used 7 of them already. So, I figured I’d better leave myself with some, in case I have other problems before the end of the year.

I asked her about using the mini trampoline we have, and also a little stepper and an exercise ball. Her concerns had to do with balance, but other than that, she thought they would be fine. She said the stepper was a particularly good one for a PWP, because of the repetitive alternating motion. Of course she cautioned me to go slow about adding minutes to it, and to rest every other day or every two days. She’s very emphatic about reminding me that the Parkinson’s means I have to rest my muscles more than other people would need to. But she emphasized that I need to be on a regular exercise program the rest of my life.

I did start on the Requip again yesterday. Even though I’ve been doing all this exercise and my legs are definitely stronger, I’m still walking very slowly. It’s called Bradykinesia, and it’s always been my main Parkinson’s symptom. Requip has some pretty uncomfortable side effects, as most of the PD meds do, it seems, so I really tried to do without it. But I just don’t think the Zelepar is enough on its own. Dr. S. told me to use my own judgment on starting it back, so I’ve decided it’s time.

I did get nauseated before lunch yesterday and I had a headache last night. Plus, this morning, I got light headed while I was taking pictures for our eBay listings. I stood still too long, I guess. Anyway, I had to stop and sit down, as I broke out in a cold sweat and could feel myself getting woozy. The worst side effect for Requip, though, is compulsive behavior – if that starts up again I won’t be able to use it, for sure.

The PT worked me pretty hard yesterday, knowing it was my last visit, and I was very uncomfortable last night. I ended up taking 2 Lortab to stop the pain in my legs. At least that meant I got a good night’s sleep! They don’t seem to be as sore today, so that’s good.

I’m having the MRI today at a different place, called a Stand Up MRI. That will be a new experience. It makes me wonder if that was chosen to get a different view of my knee, as there is a regular tunnel MRI place in the same building with my doctor.

I just realized that I forgot to call the Orthopedist’s office yesterday to make the follow up appointment. I’m really having a hard time remembering to do everything that needs to be done nowadays. Hubby tries to help me keep it all straight, and I make lists like crazy. I’ve even started using the task reminders on my Outlook program to try to help. Of course I have to remember to put the reminders in the program LOL!

I got an email from the other PT patient who has Neuropathy last night, and of all things, we live in the same town!!! I’ll be doing some research on her particular type of Neuropathy and adding links to it, if I can find anything specific for her. I wonder if she lives anywhere near the EPA toxic site, the way we do????? She’s in far worse shape than I am, and the doctors don’t know what’s causing her problems, either. And she’s young. I’ve added her to my prayers, and I hope she and I can continue to correspond.

It was a day of changes yesterday, but hopefully they will be good changes. Only time will tell.

Posted in Uncategorized | Tagged balance, Bradykinesia, difficulty walking, dopamine agonist, EPA, exercise, knee, MRI, nausea, pain, Parkinson's, peripheral neuropathy, Physical Therapy, PWP, Requip, toxic chemicals, Zelepar | Leave a reply

Peripheral Neuropathy Rears Its Ugly Head

Day by Day with a Movement Disorder Posted on April 16, 2007 by DBApril 16, 2007 8

I went to the Physical Therapist this morning for evaluation of my knee and shoulder problems. The news was not good. It seems that I have significant weakness in my right leg and hip muscles, and also in my left hip muscles. My hand strength was markedly less in the right hand than the left, but that didn’t surprise me.

She said it was no wonder I was having trouble with my knee, or with walking, as my muscles were so very weak. She does not want me to walk so far at the track, but to concentrate on walking with full use of my hip muscles. I had already realized that I wasn’t doing that. When I do take a full stride from the hip I feel like I’m drunk, with a wobbly unsteady sensation. I don’t know any other way to describe it, and I look drunk, too. She wants me to use my cane on a regular basis, because she doesn’t want me to reinforce my unnatural gait. I’m to see her two more times this week, plus she’s given me a set of exercises to do here at home.

She thinks the knee is so irritated because the muscles that should be providing support just aren’t doing their job well at all. And she said the same thing about both hips. So, I’m going to be busy trying to build up what I can, before I end up on the floor LOL!!

I also had an ultrasound treatment on my knee and an electrical stimulation treatment on the shoulder and the knee, with moist heat, too. That felt wonderful, and it’s supposed to improve and speed up the healing process.

The PT is a very nice lady, and I felt comfortable with her immediately. It’s just as well, as it sounds like I’m going to be going there for awhile. Of course, insurance has a lot to do with how many sessions they’ll let me have, so I need to learn as much as I can about how to do the exercises at home.

Posted in Uncategorized | Tagged balance, cane, difficulty walking, exercise, gait, knee, peripheral neuropathy, Physical Therapy, torn cartilage, walker | 8 Replies

Tremors Galore!!

Day by Day with a Movement Disorder Posted on February 22, 2007 by DBJune 4, 2020 10

Don’t let anyone give you the impression that everyone who has Parkinson’s reacts the same way to the loss of dopamine in the brain. I’m one of those whose main symptom is Bradykinesia, which means without medicine I can barely get my legs to move at all. My upper body movements are slower and less coordinated, but my lower body simply has no clue what my brain is telling it to do. This effects my walking, balance, and my digestive system muscles. Something as simple as standing through the verses of a song in church can be very difficult for me to do. I’m also having lots of problems sleeping, no matter how tired I am.

Unlike the stereotypical image of a PWP, I have not had tremors. Well, I can’t say that any more. Yesterday evening I noticed a rhythmic series of what felt like shivers to me, but I wasn’t cold. I thought it was nerves, as things have been quite stressful around here lately. But when I tried to go to sleep last night, those shivers turned into full blown tremors. Not only my legs, but for awhile there, my whole body was uncontrollably shaking. These are called resting tremors, as they immediately stopped when I raised both legs. As soon as I put my legs back down – they would start up again. Yep, that’s Parkinson’s tremors, alright. Something else to talk to the Neurologist about next week.

I have decided not to add the Requip to the Zelepar, since the doctor’s appointment is so close, but if I do the shake, rattle, roll thing again tonight, I may change my mind. Just as a point of information that I find extremely odd, PWP don’t have tremors in their sleep!! Weird, isn’t it??

Posted in Uncategorized | Tagged balance, Bradykenisia, coordination, difficulty walking, elimination difficulties, gait, insomnia, Parkies, Parkinson's, PWP, Quality of Life, Requip, stomach, Zelepar | 10 Replies

Zelepar is Working Much Better, Insomnia Is Still a Challenge

Day by Day with a Movement Disorder Posted on January 26, 2007 by DBJanuary 26, 2007  

Evidently the reason I was not getting good results with the Zelepar was due to the strep infection. (I did get a refill on the antibiotic, so my throat continues to improve.) This time, my walking is quite normal, and so is my balance. I am taking the second dose earlier than I did last time, as I think it was one of the factors that was keeping me from sleeping. So this has been a pleasant surprise, and a welcome result.

As for sleeping, that’s been, shall we say, interesting? My Neurologist did not want me to stay on the Ambien CR continuously, although he did refill the prescription. So, I figured I’d better find some other way to get some sleep. It wasn’t working all that great any more, anyway.

Daddy has been taking one or two Tylenol PM for years, so I figured I’d give it a try. I tried two pills for two nights, then cut back to one pill. I was still waking up after a few hours, but went back to sleep quicker. I was getting more hours sleep with the Tylenol than I had been recently with the prescription for Ambien. Go figure. But, I felt drugged for several hours in the morning.

Time to try something else, right? I figured it was time I found out just how much sleep I would get without any sleep aid. The first night I got very little sleep, and wasn’t even sleepy the next day. But after that first night, I’ve been sleeping just about as much as I did with the Ambien. So, I’m just going to do without, saving the Ambien CR for special situations. That way, maybe I’ll get the longer sleep time, the way I did the first few nights I took it.

Posted in Uncategorized | Tagged Ambien CR, balance, difficulty walking, gait, insomnia, Neurologist, Parkinson's, strep throat, Tylenol PM, Zelepar | Leave a reply

Tummy Improvement OR Walking Faster?

Day by Day with a Movement Disorder Posted on January 6, 2007 by DBJanuary 6, 2007 8

I’ve been on the new Zelepar medicine for several days now, and my digestive system is behaving just fine. I don’t seem to be getting quite as much help with my gait as I did with the Requip or Sinemet, however, but I’m still on the samples. When I go back to the Neurologist next Friday, it may be that he will order a prescription for a higher dose or more doses, which might make the difference. Anyway, even if the dose stays where it is now, it seems like a reasonable trade off between stomach problems and balance and walking problems. I’d love to walk better, but I can live with it the way it is now, if I have to. It’s nice not to spend part of every day miserable, with a hot pad on my tummy!

I said at first the Zelepar didn’t taste bitter, however, I’d better amend that evaluation. Yes, it is bitter, but not enough to bother me, anyway. (The trick is to be sure you place it under, not on, the tongue.) It dissolves under my tongue so quickly that it’s just a few seconds, and I can swallow it. You’re not allowed to drink or eat anything for at least 5 minutes before or after taking it, but my saliva quickly washes the taste away.

We’re still staying with my Daddy, which means I spend most of my days and every night in a hot house. We tried to find a compromise temperature for the thermostat, but at 101, he gets too cold, while we’re still sweltering. I have noticed that I’m having more trouble with the heat this week, since I’ve been on the Zelepar, than I was before I started taking it. I’m getting what feels exactly like hot flashes several times a day, and I’ve been past that stage for some time now. I have read that Parkinson’s can mess with the body’s regulation of internal temperature, so I guess that’s what’s happening to me right now. Or is it because of the Zelepar? I really don’t know.

I was on Requip before starting the Zelepar. Requip is a dopamine agonist, but Zelepar is an MAO-inhibitor, so they don’t attack the PD symptoms the same way. There’s big news in the Birmingham News today that a doctor at UAB is close to getting FDA approval for a patch version of a dopamine agonist. That will be good news for me, as the Requip did a better job of improving my balance and walking than it looks like the MAO-inhibitors are going to. I’m all for any PD med that I don’t have to swallow!! So this is something else for me to be hopeful about.

It’s great to see that there is good news on the horizon for the large number of people who really suffer with this disease. My own symptoms and discomfort level are so mild compared to people who have had Parkinson’s for years. I pray that all this new research may bring them relief in the near future, instead of years from now.

Posted in Uncategorized | Tagged balance, care giving, difficulty walking, dissolves, dopamine agonist, gait, Mao Inhibitor, Neurologist, Parkinson's, patch, Requip, stomach, swallowing, Zelepar | 8 Replies

My Digestive System Is Behaving! Not So Sure about Us??

Day by Day with a Movement Disorder Posted on December 31, 2006 by DBDecember 31, 2006 6

It looks like the Gastroenterologist has found the right combination to get my digestive system working again in a manageable way. I haven’t had any pain or bloating now for several days, and I’ve been able to eat some things I wouldn’t have dreamed of trying just last week. I still don’t have an appetite, but I still need to lose weight, too! So I’ll count that as a blessing for right now.

We had our Date Day today, instead of yesterday, because our respite care giver couldn’t come yesterday. We had an enjoyable day together, not really doing much, but just relaxing. With my balance as wacky as it is right now, there’s not much else we could do.

Daddy, DH, and I had our first big flare up of tempers this evening. It was just a matter of time before it happened. We’ve been trying to stall it by getting out of the house a couple of days each week, but it was inevitable.

Daddy hates the idea of having anybody in his house, doing things he would normally be doing, or changing his routines. He’s been independent too long to take easily to having DH and me here, and certainly to having Frances here two days a week. And he hates not being able to take care of himself any more.

We’ve understood how he felt, so we’ve been biting our tongues ever since he fell, as his bitterness shows through in almost everything he says to us. Hopefully this show of temper on all our parts will clear the air for a little while, but that remains to be seen.

So my relaxing day had a somewhat dramatic end, but as thick as the tension has been around here, it may well have been for the best in the long run. I can only hope so.

Posted in Uncategorized | Tagged balance, bloating, care giving, difficulty walking, elimination difficulties, Friday Date Day, Gastroenterologist, Parkinson's, Quality of Life, respite care, stomach, weight loss | 6 Replies

Tapering Off Requip

Day by Day with a Movement Disorder Posted on December 29, 2006 by DBDecember 29, 2006 6

When I went to my Neurologist last Tuesday, we decided I would stop taking the Requip, since it was probably the cause of all my stomach problems, other than the PD itself. Also, it was the likely culprit for my hair loss. So, Dr. S. told me to taper off the Requip before I changed over to the samples of Zelepar he gave me. That meant last week I only had two pills a day, instead of the usual three. Starting Tuesday of this week, I’ve only been taking one a day.

Dopamine is the brain chemical that controls muscle movement, and that’s the one that people with Parkinson’s no longer make enough of. Requip tricks the brain into accepting the chemical in it as a substitute for the dopamine, so it’s called a dopamine agonist. Now that I’m down to one pill a day, I can really tell it! My balance is terrible, and my walking is stilted and jerky.

As long as DH can take over the care giving tasks I’m not up to, I’ll continue to do as much as I can to help Daddy. We’ve only got to make it until next Wednesday, and then I can start taking the new medicine. Zelepar, a special form of the medicine called Selegiline, is a different type of Parkinson’s medicine entirely. It is an MAO-inhibitor. I’ve read what that means a dozen times now, but I still don’t understand it well enough to put it in my own words LOL.

The reason Dr. S. is trying this particular prescription is that it dissolves on the tongue and does not go through my digestive system. It goes straight into the blood stream. With the improvement in stomach comfort that I’m seeing from the Miralax and glycerin suppository combination, I’m hoping this new medicine will be the perfect one for me for the time being.

I do know that at some point I will have to go back to taking Sinemet, which was the first medicine I took. It nauseated me, too, but I’ll cross that bridge when I get to it, because there is a patch form of it in drug trials now.

So for the next few days I’ll be weaving and lurching around here like I’m drunk, but I can put up with it, knowing there’s something new to try just days away. I am ever thankful to God that there are so many researchers working to find new ways of fighting the symptoms of this disease, working on ways to slow its progress down, and ultimately to cure it.

Posted in Uncategorized | Tagged balance, brain, care giving, difficulty walking, dissolves, dopamine agonist, glycerin suppositories, hair loss, Mao Inhibitor, Miralax, nausea, Neurologist, Parkinson's, Requip, Selegiline, Zelepar | 6 Replies

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