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Daily Journal with Mitochondrial Myopathy

Day by Day with a Movement Disorder

My Journey with a Mitochondrial Disease - "But they that wait upon the LORD shall renew their strength; they shall mount up with wings as eagles; they shall run, and not be weary; and they shall walk, and not faint." Isaiah 40:31 KJV

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Diagnosis in 2006 - Parkinson's Disease and Peripheral Neuropathy, then in 2007 - Essential Myoclonus. Finally in 2011, after a muscle biopsy, I was diagnosed with Mitochondrial Myopathy as well as Peripheral Neuropathy.

Share my journey - coping with the testing, the medicines, nutrition, digestion problems, exercise, the emotions, uncertain diagnoses and no telling what else!

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Went Off PD Meds Temporarily

Day by Day with a Movement Disorder Posted on December 23, 2007 by DBDecember 23, 2007  

I had my last PD medicine around 3:00PM Friday, so I have been without now for about 48 hours. I don’t know how much of those meds are still in my system, but I suspect there’s not much left.

So, how am I doing? Well, my right foot particularly, and the left to some extent, are shaking some, particularly when I stand in one place for more than just a few seconds. The wobbling foot and knee make my whole body rock rhythmically. It’s nowhere near as bad as it looked in Dr. S’s office Wednesday, but I was very nervous then, so the exaggerated gait was not overly surprising.

My right hand takes a notion to tremble off and on all day long, but I can usually stop it temporarily by thinking about it. Usually, I just start to jerk somewhere else, when I get one tremor stopped by relaxing and concentrating on just that one area. The facial and tongue tics seem to be worse, too, with me off the PD meds. Generally, I see an increase in jerkiness that moves from place to place as I consciously try to stop it elsewhere.

We haven’t told anyone in the family about this possible change in diagnosis, and don’t intend to, until it has been confirmed, and hopefully, we have a name for what is wrong with me.

I am going back on my Zelepar and Requip at 3:00PM today, and will stay one them at least until all the holidays are over with, and I am dismissed from PT. I probably will try going without again in February, just to see how I am doing then.

I wrote once before that having a neurological disease is like being in a clinical trial of ONE. It becomes very difficult to manage all the possible variables, and come to any kind of conclusion about the level of disability and what improves or aggravates the symptoms.

Posted in Uncategorized | Tagged coordination, diagnosis, difficulty walking, gait, peripheral neuropathy, Physical Therapy, prescriptions, psychosomatic, Quality of Life, Requip, symptoms, tests | Leave a reply

Sitting MRI and a Full Night’s Sleep

Day by Day with a Movement Disorder Posted on December 13, 2007 by DBDecember 13, 2007 2

Well, I had my Standing MRI on my neck yesterday. I was having some strong tremors when I got there, so the technician changed it to a Sitting MRI! LOL!! He also put a lightly restraining halo on my head, and I managed to stay still through the whole 30 minutes. He said I did just fine.

Of course I won’t find out anything until next week probably. I’m guessing that he will prescribe Physical Therapy again, particularly since I had such a terrible reaction to the Celestone steroid shot for my poison ivy. It depends on just how much damage he sees, I guess.

I have my Neurologist appointment next week, so I will be talking to him about how I should proceed. He may have me stop taking the Zelepar, as that seems to be the med that gives me the most interaction warnings. It does not play well with others!

I have an appointment with my Sleep Apnea Specialist next week, too. He should be dismissing me, hopefully. I am sleeping a full 8 hours almost every night now. And it has made a miraculous difference in my daytime sleeping. Actually, I’m not having ANY daytime sleeping problems, now. I can ride in the car for hours now, and still carry on a conversation with my DH. It’s been years since I could do that. No more jerking awake at the computer from a few seconds of sound sleep out of nowhere. And, I am still on the Requip that gets blamed for this side effect. It wasn’t the medicine after all for me. I was just sleep deprived!

It’s so gratifying to see improvement even in one area of my health. And I have high hopes that Dr. J will fix the pain and stiffness in my neck.

Posted in Uncategorized | Tagged Degenerative Disk Disease, dental appliance, drug interaction, insomnia, MRI, muscle spasms, Neurologist, pain, Parkinson's, Physical Therapy, Quality of Life, Requip, Sleep Apnea, tremors, Zelepar | 2 Replies

Tummy in Rebellion

Day by Day with a Movement Disorder Posted on October 2, 2007 by DBOctober 2, 2007 6

Warning: This post is not for the weak stomached!

Today did not go well at all. I followed my list of med times, trying to spread out all the doses as much as possible. I was careful to take the ones that needed to be with food, and the one that needed to be without food at appropriate times.

Before I could finish sipping my hot tea this morning after breakfast, I moved to get up from the sofa to go to the bathroom, and all the liquids I had taken in over the last hour – juice, water, and tea – all came up explosively all over me and the sofa, propelled by all this gas I have. It’s as if my stomach is stopped up at the bottom and couldn’t hold it all. That is called Gastroparesis, which means slowing of the emptying of the stomach, and is quite likely part of my problem. Really, every part of my digestive tract shows signs of weakening, so I shouldn’t be surprised when something like this happens. That didn’t make it any less upsetting, though, as DH had to quickly do a wash before all that acid ruined my clothes, while I took a bath, and we had to try to get our sofa cleaned up, too. And, I’ve stayed nauseated most of the day, just as I did when I tried to take Sinemet last year.

From what I’ve read from other PWP, many people get over the nausea fairly quickly when they start Sinemet, so I sure hope I will be able to tolerate it this time. I was much sicker with the GERD last year when I tried to take it than I am now, so there is reason to be optimistic, which is what I choose to be.

I see my Gastroenterologist tomorrow, and I have an appointment with my Neurologist next Friday, so maybe I will know what needs to be done soon to get the benefit, and not the side effects, of my meds.

Posted in Uncategorized | Tagged gas, GERD, Lodosyn, nausea, Parkinson's, Quality of Life, Requip, Sinemet, Sucralfate, Zelepar | 6 Replies

Day One with Sinemet

Day by Day with a Movement Disorder Posted on October 2, 2007 by DBOctober 2, 2007 6

Yesterday was the first full day of taking Sinemet again, as well as the Requip and Zelepar I was already on. I also had the Lodosyn and Sucralfate I requested from the ER doc, so that the Sinemet had a better chance of not making me so nauseated, the way it did last year. I started the morning hardly able to feed myself or walk, but ended the day almost back to my normal state. That was a huge relief, to say the least!!!

I also talked to my Gastroenterologist last night, but without any real conclusion to my gas and belching problem, or my elimination difficulties. He basically just asked me a lot of questions, most of which I could not give him any clear cut answer to, and told me to go on and make an appointment with him. I told him about the ER trip, and how I had been delaying my Neuro appointment, waiting for a diagnosis. He said to go on and make the Neurologist appointment, so I’ll do that today. The fact that he has taken so long going over all the diary I gave him, plus his obvious quandary as to what is going on, leads me to think that a serious diagnosis is not jumping out at him as likely. That is what I’m going to assume, anyway.

The comical part of all this was trying to figure out a schedule to add in three more meds, taking into account all the restrictions on timing and eating and nearness to other meds that each one has. I finally wrote out today’s schedule, and I’m taking one or more medicines today at 5AM, 6, 7:30, 9, 11, 12, 1:15, 3, 5, 6:30, and 8PM! And that doesn’t count the Myralax that goes on my cereal or the glycerin suppositories I use! You should see the size of my pill boxes!! Oops, my timer just went off…. time to go take medicine LOL!

Well, I’m back. I just took the Sucralfate, a hog pill that I had trouble swallowing yesterday. Last night we cut it in half, but I still choked on it, because it’s so dry going down. So, this morning I soaked the two halves in a tablespoon of water, and swallowed that. That was much easier, although I can still feel the dry scratchiness down my throat. That’s one of my new stomach protector meds, so I have to take it, uncomfortable or not.

Each day is a new adventure with this PD, with some days being hopeful and others being miserable. Thank goodness I don’t often get as down as I was Sunday night. I thank God for that!! And, I thank you for caring enough to say an encouraging word, too, as I surely need it.

Posted in Uncategorized | Tagged choking, depression, difficulty walking, elimination difficulties, gas, Gastroenterologist, God, Lodosyn, Parkinson's, Quality of Life, Requip, Sinemet, stomach, Sucralfate, tremors, Zelepar | 6 Replies

Insomnia Is on the Prowl AGAIN

Day by Day with a Movement Disorder Posted on May 12, 2007 by DBMay 12, 2007  

Looks like the Requip has my bout with insomnia going full force again. I didn’t get to sleep until after 11 last night, but I’ve been wide awake since 2:30 this morning. It’s been pretty much like this now ever since I started back on this particular medicine. I do have some sleeping pills, but I’ve resisted taking them, hoping my system would adjust. But tonight, I will definitely be taking one.

I do get a lot done when I’m in one of these moods, though! ROTFL I’m just about ready to change the listings on all our current eBay items to reflect all the changes the Post Office is making in Rate Classifications and prices. Just a word of warning to all of you …. don’t be surprised if it costs considerably more to get something mailed to you from now on. The PO has really raised their prices tremendously, for some package situations as much as 700%!!!!

We bought a pedometer for me the other day, but I’m not convinced that it is counting every step I take. If it is, I’m not moving nearly enough in a day. DH isn’t having any trouble at all going over 10,000 steps a day, and I barely went over 1,000!

My exercise program is coming along nicely, though, and my legs continue to gain in strength. I’ve been trying to understand exactly how to improve my posture and gait, based on the Chi Walking book I mentioned several posts ago. I wish I had someone who could just show me how, instead of trying to figure it out from pictures and words. I really don’t have a very good kinesthetic sense .. in other words, it’s hard for me to really tell where my body is. But that’s nothing new …. I’ve always been that way, even as a child. I remember struggling to try to learn how to do a summersalt, and giving up finally. The Tai Chi routine does help me to be aware of where my body position is, and I’ve started doing that when we go to the track. DH walks 2+ miles in the time it takes me to do all my exercises, walk a quarter mile, and do my Tai Chi, with maybe a little time left over to clean out the car of all the junk it seems to accumulate so quickly, or to read a little. It’s a great way to start the day off, with a feeling of accomplishment right off the bat.

So far, the only obsessive behavior I’ve noticed is that my craving for chocolate has gotten out of hand again. I did without any for such a long time, but when Daddy died I went back to eating it every day. I’m not supposed to eat it at all, because of the GERD I have. I’m really very good about avoiding everything else the Gastroenterologist has put on my banned list, but when I’m stressed for depressed, I have to have my chocolate. Nothing else will satisfy that craving. And I’ve always been that way. I can remember getting into trouble as a child on more than one occasion, because Mama would go to bake a cake, and I had eaten the bitter dark chocolate in the refrigerator. So when I read things about how chocolate contains chemicals that relieve stress, I believe it!

Posted in Uncategorized | Tagged Bradykinesia, exercise, gait, Gastroenterologist, GERD, insomnia, knee, OCD, Requip, stress, Tai Chi | Leave a reply

Parkinson’s Patch Approved in USA

Day by Day with a Movement Disorder Posted on May 10, 2007 by DBMay 10, 2007 4

Neupro, a dopamine agonist delivered in patch form, has been available in Canada and Europe for some time, but now it has been approved in the USA. The Requip I am on is a dopamine agonist, so I should be a good candidate for the patch.

I was disappointed on doing some research to find that nausea is still one of the more common side effects. I was hoping that my tummy would not be involved, since it’s not a medicine that is swallowed. There’s also a fairly high incidence of irritation at the patch site, and users are not supposed to put the patch in the same place more often than 14 days apart. Most of the other side effects are true of just about all the Parkinson’s medicines, from dizziness to low blood pressure on standing. As a dopamine agonist, there is a certain level of risk of obsessive behavior and also of suddenly falling asleep. Driving can be risky. Thank goodness we’re both retired, because my not driving has really not been a real problem for us.

So, although I had planned on bugging the Neurologist to change me to the patch as soon as it was approved, now that I know a little more about it, I probably won’t be in such a hurry to push for it.

If anyone reads this who has been on Neupro, or is now on it, please leave a comment about your results and/or side effects.

Posted in Uncategorized | Tagged dopamine agonist, nausea, Neupro, prescriptions, Requip, stomach | 4 Replies

Standing MRI & A New Friend

Day by Day with a Movement Disorder Posted on May 9, 2007 by DBMay 9, 2007 2

I had the standing MRI yesterday, and that was quite a bit different from the lying down kind. First of all, it would be much better for anyone who is claustrophobic, as I was not closed in, and they actually had a big screen TV set up so I could watch it.

As far as my procedure was concerned, it was not very comfortable. The whole point was to take the MRI while I was putting weight on the knee, so I had to stand at about a 60 or 70 degree angle, I would guess, and be very still for about 30 minutes. By the time it was over my knee was really complaining, but it was worth every moment of it, if it gets them a better idea of what’s going on in there. I still don’t expect it to be torn cartilage, but soon I will know. Their brochure showed pictures of regular MRI views vs their stand up kind, with obvious disk problems that didn’t show up when the patient was lying down. I may ask for that kind the next time I have to have one on my neck or back, for just that reason. I’ll see the Orthopedist next week to get the report on it.

I’ve added the beginnings of a section on Radial Neuropathy to my side bar, not because I have that, but because I’ve recently started emailing back and forth to a new friend who has it. She and I live in the same small town, I taught her husband, know her MIL, and we’re even members of the same church. And neither one of us knew each other LOL!! It was the Physical Therapist we’ve been going to, who gave her my blog URL, that got us together. She promises that she’ll be posting here, so hopefully she can make contact with others who have problems more similar to hers. My Neuropathy is most noticeable in my legs, although my hands and arms are involved, too. Hers is severe, but I’ll leave it to her to explain it.

I noticed the nausea from the Requip about 11:00AM again yesterday, but a few crackers stopped it. I’m still getting sleepy at the wrong time, as I nodded off early last night watching TV, and I’ve been up since 4:00AM. Actually, I woke up a little after 3:00, but I made myself stay put, thinking I would go back to sleep. No such luck.

I can’t tell any difference in my gait yet, but it may take a week or so before I would notice anything, anyway. I don’t remember reading anything about how long it takes Requip to take effect, so I’ll have to try to do some research on that.

Oh, remember when I was having so much trouble typing? That has definitely improved. It must have been the stress of dealing with Daddy that was making that worse. Parkinson’s folks don’t handle stress as well as others do. I still make more mistakes than I’d like, but nothing like it was for awhile there.

I’ve done my morning exercises, but we’re still not walking at the track. Hubby’s poison ivy is getting worse, not better, and he’s so stubborn I can’t get him to go to the doctor about it. So he’s just slathering on the anti-itch medicines I already had in the house, and he’s trying to stay cool.

Speaking of cool, my temperature regulator is all off whack. I’ll have hot flashes one minute and be freezing the next. I’m putting my jacket on and pulling it off constantly!! This is a Parkies thing, too, so there’s not much else I can do about it.

I’ll spend the day today writing descriptions and finishing the pictures I took this morning, so I can put some new items on eBay tonight. DH has gone grocery shopping, a regular Wednesday morning routine of his, and a chance for him to stop and chat with his buddies. I guess that pretty well catches me up for the day. I hope you are having a good day, too.

Posted in Uncategorized | Tagged Bradykinesia, eBay, exercise, gait, insomnia, knee, MRI, nausea, Orthopedist, Parkies, peripheral neuropathy, Physical Therapy, Radial Neuropathy, Requip, stress, torn cartilage, typing | 2 Replies

Starting Requip Again – Stopped Physical Therapy

Day by Day with a Movement Disorder Posted on May 8, 2007 by DBMay 8, 2007  

Yesterday was my last time for Physical Therapy on my knee for now. I called my insurance company, and they only allow 15 PT visits a year, unless THEY approve the extra ones, and I’ve used 7 of them already. So, I figured I’d better leave myself with some, in case I have other problems before the end of the year.

I asked her about using the mini trampoline we have, and also a little stepper and an exercise ball. Her concerns had to do with balance, but other than that, she thought they would be fine. She said the stepper was a particularly good one for a PWP, because of the repetitive alternating motion. Of course she cautioned me to go slow about adding minutes to it, and to rest every other day or every two days. She’s very emphatic about reminding me that the Parkinson’s means I have to rest my muscles more than other people would need to. But she emphasized that I need to be on a regular exercise program the rest of my life.

I did start on the Requip again yesterday. Even though I’ve been doing all this exercise and my legs are definitely stronger, I’m still walking very slowly. It’s called Bradykinesia, and it’s always been my main Parkinson’s symptom. Requip has some pretty uncomfortable side effects, as most of the PD meds do, it seems, so I really tried to do without it. But I just don’t think the Zelepar is enough on its own. Dr. S. told me to use my own judgment on starting it back, so I’ve decided it’s time.

I did get nauseated before lunch yesterday and I had a headache last night. Plus, this morning, I got light headed while I was taking pictures for our eBay listings. I stood still too long, I guess. Anyway, I had to stop and sit down, as I broke out in a cold sweat and could feel myself getting woozy. The worst side effect for Requip, though, is compulsive behavior – if that starts up again I won’t be able to use it, for sure.

The PT worked me pretty hard yesterday, knowing it was my last visit, and I was very uncomfortable last night. I ended up taking 2 Lortab to stop the pain in my legs. At least that meant I got a good night’s sleep! They don’t seem to be as sore today, so that’s good.

I’m having the MRI today at a different place, called a Stand Up MRI. That will be a new experience. It makes me wonder if that was chosen to get a different view of my knee, as there is a regular tunnel MRI place in the same building with my doctor.

I just realized that I forgot to call the Orthopedist’s office yesterday to make the follow up appointment. I’m really having a hard time remembering to do everything that needs to be done nowadays. Hubby tries to help me keep it all straight, and I make lists like crazy. I’ve even started using the task reminders on my Outlook program to try to help. Of course I have to remember to put the reminders in the program LOL!

I got an email from the other PT patient who has Neuropathy last night, and of all things, we live in the same town!!! I’ll be doing some research on her particular type of Neuropathy and adding links to it, if I can find anything specific for her. I wonder if she lives anywhere near the EPA toxic site, the way we do????? She’s in far worse shape than I am, and the doctors don’t know what’s causing her problems, either. And she’s young. I’ve added her to my prayers, and I hope she and I can continue to correspond.

It was a day of changes yesterday, but hopefully they will be good changes. Only time will tell.

Posted in Uncategorized | Tagged balance, Bradykinesia, difficulty walking, dopamine agonist, EPA, exercise, knee, MRI, nausea, pain, Parkinson's, peripheral neuropathy, Physical Therapy, PWP, Requip, toxic chemicals, Zelepar | Leave a reply

Lots to Do Settling Daddy’s Estate

Day by Day with a Movement Disorder Posted on March 29, 2007 by DBMarch 29, 2007 12

This is the second time I’ve been the executor of an estate, but Daddy’s is much more involved than Pop’s was. Luckily, we have a niece who is a lawyer, so I’ll have some help when I’m ready. I’ve tried researching what I need to do on the Internet, and I’ve been surprised at how little help I could find. Everything seems to be geared toward Estate Planning, rather than settling an estate.

April 15th is getting closer, too, and I’ve just not been up to dealing with important numbers. I did get a good start today, though. Starting is half the battle for me, as I find I’ve become quite the procrastinator in the last few years. I don’t know if that’s a sign of old age LOL, stress, or Parkinson’s!

We walked again this morning, but I was slow as mud. I made it around for a half mile, using the walker. I’ve been using the walker all this week, but I depended on it more today, as I could feel the tightness in my shoulders when I stopped. That slow as mud feeling is the first Parkinson’s symptom I had, so it’s looking less and less like I’ll be able to continue on just the Zelepar. The Neurologist told me I could go back on the Requip as well, if I felt like I had to. I’ve resisted, because the Requip gave me stomach troubles last time. Well, I had stomach trouble when I was on the Requip – that doesn’t automatically mean the Requip was causing it. It’s that uncertainty that has kept me trying to do without it. I’m just not ready to cope with stomach side effects yet. Maybe next week.

I taught 4th and 5th graders for 25 years, but I’ve seen the “Smarter than a Fifth Grader” TV show a couple of times since I’ve been back home. It’s scary how much my mind goes blank on stuff I know I should know. I hope it’s just remnants of caregiver burnout, and not the PD effecting my mental abilities. Stress can really do a number on such tasks, so I’m trying really hard to relax as much as I can. But getting things accomplished is part of what’s needed to lower my stress level, too, so it’s a matter of finding a balance, I guess.

I continue to be uplifted by all the loving comments. You all really are helping. Just a thought for you, if you need to send a sympathy card to someone. One of our friends included a neatly cut out copy of Daddy’s Obituary notice in their card. It was very much appreciated.

Posted in Uncategorized | Tagged care giving, Daddy, death, difficulty walking, exercise, Income tax, nausea, Parkinson's, procrastination, Requip, settling an estate, stomach, stress, walker, Zelepar | 12 Replies

Tremors Galore!!

Day by Day with a Movement Disorder Posted on February 22, 2007 by DBJune 4, 2020 10

Don’t let anyone give you the impression that everyone who has Parkinson’s reacts the same way to the loss of dopamine in the brain. I’m one of those whose main symptom is Bradykinesia, which means without medicine I can barely get my legs to move at all. My upper body movements are slower and less coordinated, but my lower body simply has no clue what my brain is telling it to do. This effects my walking, balance, and my digestive system muscles. Something as simple as standing through the verses of a song in church can be very difficult for me to do. I’m also having lots of problems sleeping, no matter how tired I am.

Unlike the stereotypical image of a PWP, I have not had tremors. Well, I can’t say that any more. Yesterday evening I noticed a rhythmic series of what felt like shivers to me, but I wasn’t cold. I thought it was nerves, as things have been quite stressful around here lately. But when I tried to go to sleep last night, those shivers turned into full blown tremors. Not only my legs, but for awhile there, my whole body was uncontrollably shaking. These are called resting tremors, as they immediately stopped when I raised both legs. As soon as I put my legs back down – they would start up again. Yep, that’s Parkinson’s tremors, alright. Something else to talk to the Neurologist about next week.

I have decided not to add the Requip to the Zelepar, since the doctor’s appointment is so close, but if I do the shake, rattle, roll thing again tonight, I may change my mind. Just as a point of information that I find extremely odd, PWP don’t have tremors in their sleep!! Weird, isn’t it??

Posted in Uncategorized | Tagged balance, Bradykenisia, coordination, difficulty walking, elimination difficulties, gait, insomnia, Parkies, Parkinson's, PWP, Quality of Life, Requip, stomach, Zelepar | 10 Replies

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